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Chromatin occupancy and target genes of the haematopoietic master transcription factor MYB

Abstract The transcription factor MYB is a master regulator in haematopoietic progenitor cells and a pioneer factor affecting differentiation and proliferation of these cells. Leukaemic transformation may be promoted by high MYB levels. Despite much accumulated molecular knowledge of MYB, we still l...

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Auteurs principaux: Roza B. Lemma, Marit Ledsaak, Bettina M. Fuglerud, Geir Kjetil Sandve, Ragnhild Eskeland, Odd S. Gabrielsen
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2021-04-01
Collection:Scientific Reports
Accès en ligne:https://doi.org/10.1038/s41598-021-88516-w
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