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Experimental elongation of telomeres extends the lifespan of immortal x normal cell hybrids.

Hybrids between immortal cells that express telomerase and normal cells that lack telomerase have a limited lifespan. We demonstrate that telomerase is repressed in such hybrids. Treatment of immortal human cell lines with certain oligonucleotides resulted in telomere elongation. We took advantage o...

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Dettagli Bibliografici
Autori principali: Wright, W E, Brasiskyte, D, Piatyszek, M A, Shay, J W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC450086/
https://ncbi.nlm.nih.gov/pubmed/8612598
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