Proteolytic action of thrombin is required for electrical activity-dependent synapse reduction.

Molecular mechanisms of activity-dependent synapse reduction were studied in an in vitro mammalian neuromuscular preparation. Synapse reduction in this model is activity-dependent and is substantially reduced by the broad-spectrum protease inhibitor, leupeptin, suggesting the role of activity-depend...

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Bibliografiske detaljer
Main Authors: Liu, Y, Fields, R D, Festoff, B W, Nelson, P G
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC45007/
https://ncbi.nlm.nih.gov/pubmed/7524091
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