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Roles of active site residues in LodA, a cysteine tryptophylquinone dependent ε-lysine oxidase
Site-directed mutagenesis identified residues in the substrate channel of LodA that play multiple roles in regulating K(m) values of substrates, k(cat) and the extent of biosynthesis of the protein-derived cysteine tryptophylquinone (CTQ) cofactor. Mutations of Cys448 increase K(m) values for lysine...
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| Vydáno v: | Arch Biochem Biophys |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500670/ https://ncbi.nlm.nih.gov/pubmed/26048732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2015.05.013 |
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