Tissue Inhibitor Of Matrix Metalloproteinase-1 Is Required for High-Fat Diet-Induced Glucose Intolerance and Hepatic Steatosis in Mice

BACKGROUND: Plasma levels of tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) are elevated in obesity and obesity-related disorders, such as steatosis, but the metabolic role of TIMP-1 is unclear. Here we investigated how the presence or absence of TIMP-1 affected the development of diet-indu...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Fjære, Even, Andersen, Charlotte, Myrmel, Lene Secher, Petersen, Rasmus Koefoed, Hansen, Jakob Bondo, Tastesen, Hanne Sørup, Mandrup-Poulsen, Thomas, Brünner, Nils, Kristiansen, Karsten, Madsen, Lise, Rømer, Maria Unni
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500465/
https://ncbi.nlm.nih.gov/pubmed/26168159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132910
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