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Chronic Losartan Treatment Up-Regulates AT(1)R and Increases the Heart Vulnerability to Acute Onset of Ischemia and Reperfusion Injury in Male Rats
Inhibition of angiotensin II type 1 receptor (AT(1)R) is an important therapy in the management of hypertension, particularly in the immediate post-myocardial infarction period. Yet, the role of AT(1)R in the acute onset of myocardial ischemia and reperfusion injury still remains controversial. Thus...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500443/ https://ncbi.nlm.nih.gov/pubmed/26168042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132712 |
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