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Lack of Acid Sphingomyelinase Induces Age-Related Retinal Degeneration
BACKGROUND: Mutations of acid sphingomyelinase (ASMase) cause Niemann–Pick diseases type A and B, which are fatal inherited lipid lysosomal storage diseases, characterized with visceral organ abnormalities and neurodegeneration. However, the effects of suppressing retinal ASMase expression are not u...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500403/ https://ncbi.nlm.nih.gov/pubmed/26168297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133032 |
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