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Structures of potent anticancer compounds bound to tubulin
Small molecules that bind to tubulin exert powerful effects on cell division and apoptosis (programmed cell death). Cell-based high-throughput screening combined with chemo/bioinformatic and biochemical analyses recently revealed a novel compound MI-181 as a potent mitotic inhibitor with heightened...
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| Publicado no: | Protein Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500315/ https://ncbi.nlm.nih.gov/pubmed/25970265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2704 |
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