Structural analysis of a class III preQ(1) riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics

PreQ(1)-III riboswitches are newly identified RNA elements that control bacterial genes in response to preQ(1) (7-aminomethyl-7-deazaguanine), a precursor to the essential hypermodified tRNA base queuosine. Although numerous riboswitches fold as H-type or HL(out)-type pseudoknots that integrate liga...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Liberman, Joseph A., Suddala, Krishna C., Aytenfisu, Asaminew, Chan, Dalen, Belashov, Ivan A., Salim, Mohammad, Mathews, David H., Spitale, Robert C., Walter, Nils G., Wedekind, Joseph E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500280/
https://ncbi.nlm.nih.gov/pubmed/26106162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503955112
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