Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A(2)-IIA

Platelets are anucleated blood elements highly potent at generating extracellular vesicles (EVs) called microparticles (MPs). Whereas EVs are accepted as an important means of intercellular communication, the mechanisms underlying platelet MP internalization in recipient cells are poorly understood....

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Duchez, Anne-Claire, Boudreau, Luc H., Naika, Gajendra S., Bollinger, James, Belleannée, Clémence, Cloutier, Nathalie, Laffont, Benoit, Mendoza-Villarroel, Raifish E., Lévesque, Tania, Rollet-Labelle, Emmanuelle, Rousseau, Matthieu, Allaeys, Isabelle, Tremblay, Jacques J., Poubelle, Patrice E., Lambeau, Gérard, Pouliot, Marc, Provost, Patrick, Soulet, Denis, Gelb, Michael H., Boilard, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500271/
https://ncbi.nlm.nih.gov/pubmed/26106157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507905112
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