Bursty gene expression in the intact mammalian liver

Bursts of nascent mRNA have been shown to lead to substantial cell-cell variation in unicellular organisms, facilitating diverse responses to environmental challenges. It is unknown whether similar bursts and gene-expression noise occur in mammalian tissues. To address this, we combine single molecu...

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Bibliographic Details
Published in:Mol Cell
Main Authors: Halpern, Keren Bahar, Tanami, Sivan, Landen, Shanie, Chapal, Michal, Szlak, Liran, Hutzler, Anat, Nizhberg, Anna, Itzkovitz, Shalev
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500162/
https://ncbi.nlm.nih.gov/pubmed/25728770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.01.027
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