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Spatial sorting enables comprehensive characterization of liver zonation

The mammalian liver is composed of repeating hexagonal units termed lobules. Spatially resolved single-cell transcriptomics revealed that about half of hepatocyte genes are differentially expressed across the lobule, yet technical limitations impeded reconstructing similar global spatial maps of oth...

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Détails bibliographiques
Publié dans:Nat Metab
Auteurs principaux: Ben-Moshe, Shani, Shapira, Yonatan, Moor, Andreas E., Manco, Rita, Veg, Tamar, Bahar Halpern, Keren, Itzkovitz, Shalev
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751089/
https://ncbi.nlm.nih.gov/pubmed/31535084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-019-0109-9
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