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Increased IFN-α-producing Plasmacytoid Dendritic Cells (pDCs) in Human Th1-mediated Type 1 Diabetes: pDCs Augment Th1 Responses through IFN-α Production()
Increasing evidence suggests that type 1 interferon (IFN-α/β) is associated with pathogenesis of Th1-mediated type 1 diabetes (T1D). A major source of IFNα/β is plasmacytoid dendritic cells (pDCs). In this study, we analyzed peripheral blood pDC numbers and functions in at-risk, new onset and establ...
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| Izdano u: | J Immunol |
|---|---|
| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500116/ https://ncbi.nlm.nih.gov/pubmed/24973447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303230 |
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