Targeting of the CREB gene leads to up-regulation of a novel CREB mRNA isoform.

To define the role of cAMP signaling in gene control, we have generated mice with a mutation in the cAMP response element binding protein (CREB) gene. Mice carrying this mutation are viable but show an impairment in memory consolidation. In further analysis of these mice, we have found an up-regulat...

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Detaylı Bibliyografya
Asıl Yazarlar: Blendy, J A, Kaestner, K H, Schmid, W, Gass, P, Schutz, G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1996
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC450007/
https://ncbi.nlm.nih.gov/pubmed/8605879
Etiketler: Etiketle
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