Targeting of the CREB gene leads to up-regulation of a novel CREB mRNA isoform.

To define the role of cAMP signaling in gene control, we have generated mice with a mutation in the cAMP response element binding protein (CREB) gene. Mice carrying this mutation are viable but show an impairment in memory consolidation. In further analysis of these mice, we have found an up-regulat...

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Bibliografiska uppgifter
Huvudupphovsmän: Blendy, J A, Kaestner, K H, Schmid, W, Gass, P, Schutz, G
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1996
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC450007/
https://ncbi.nlm.nih.gov/pubmed/8605879
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