Protein dimerization between Lmo2 (Rbtn2) and Tal1 alters thymocyte development and potentiates T cell tumorigenesis in transgenic mice.

The LMO2 and TAL1 genes were first identified via chromosomal translocations and later found to encode proteins that interact during normal erythroid development. Some T cell leukaemia patients have chromosomal abnormalities involving both genes, implying that LMO2 and TAL1 act synergistically to pr...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Larson, R C, Lavenir, I, Larson, T A, Baer, R, Warren, A J, Wadman, I, Nottage, K, Rabbitts, T H
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC449997/
https://ncbi.nlm.nih.gov/pubmed/8605871
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky