Differential control of transcription-induced and overall DNA supercoiling by eukaryotic topoisomerases in vitro.

The global superhelical state of intracellular DNA is stringently controlled by topoisomerase action. Little is know, however, about topoisomerase-directed relaxation of localized DNA supercoiling generated by protein tracking processes such as transcription. Here we use transcription by a yeast Gal...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Wang, Z, Dröge, P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC449976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8599941/
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