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Differential control of transcription-induced and overall DNA supercoiling by eukaryotic topoisomerases in vitro.

The global superhelical state of intracellular DNA is stringently controlled by topoisomerase action. Little is know, however, about topoisomerase-directed relaxation of localized DNA supercoiling generated by protein tracking processes such as transcription. Here we use transcription by a yeast Gal...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Wang, Z, Dröge, P
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC449976/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8599941/
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