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Targeting Insulin-Like Growth Factor Binding Protein-3 Signaling in Triple-Negative Breast Cancer

Insulin-like growth factor binding protein-3 (IGFBP-3) is a key regulatory molecule of the IGF axis and can function in a tissue-specific way as both a tumor suppressor and promoter. Triple-negative breast cancer (TNBC) has high tumor expression of IGFBP-3 associated with markers of poor prognosis a...

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Vydáno v:Biomed Res Int
Hlavní autoři: Marzec, Kamila A., Baxter, Robert C., Martin, Janet L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499383/
https://ncbi.nlm.nih.gov/pubmed/26221601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/638526
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