Role of the duplicated CCAAT box region in gamma-globin gene regulation and hereditary persistence of fetal haemoglobin.

Hereditary persistence of fetal haemoglobin (HPFH) is a clinically important condition in which a change in the developmental specificity of the gamma-globin genes results in varying levels of expression of fetal haemoglobin in the adult. The condition is benign and can significantly alleviate the s...

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Bibliographic Details
Main Authors: Ronchi, A, Berry, M, Raguz, S, Imam, A, Yannoutsos, N, Ottolenghi, S, Grosveld, F, Dillon, N
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC449926/
https://ncbi.nlm.nih.gov/pubmed/8598197
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