Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1.

Using a yeast two-hybrid system we report the isolation of a novel mouse protein, mSUG1, that interacts with retinoic acid receptor alpha (RAR alpha) both in yeast cells and in vitro in a ligand- and AF-2 activating domain (AF-2 AD)-dependent manner and show that it is a structural and functional ho...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: vom Baur, E, Zechel, C, Heery, D, Heine, M J, Garnier, J M, Vivat, V, Le Douarin, B, Gronemeyer, H, Chambon, P, Losson, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC449923/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8598193/
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