DNA-PKcs phosphorylates hnRNP-A1 to facilitate the RPA-to-POT1 switch and telomere capping after replication

The heterogeneous nuclear ribonucleoprotein A1 (hnRNP-A1) has been implicated in telomere protection and telomerase activation. Recent evidence has further demonstrated that hnRNP-A1 plays a crucial role in maintaining newly replicated telomeric 3′ overhangs and facilitating the switch from replicat...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Sui, Jiangdong, Lin, Yu-Fen, Xu, Kangling, Lee, Kyung-Jong, Wang, Dong, Chen, Benjamin P.C.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Genome Integrity, Repair and Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499152/
https://ncbi.nlm.nih.gov/pubmed/25999341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv539
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