Post-conversion targeted capture of modified cytosines in mammalian and plant genomes

We present a capture-based approach for bisulfite-converted DNA that allows interrogation of pre-defined genomic locations, allowing quantitative and qualitative assessments of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) at CG dinucleotides and in non-CG contexts (CHG, CHH) in mammalia...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Li, Qing, Suzuki, Masako, Wendt, Jennifer, Patterson, Nicole, Eichten, Steven R., Hermanson, Peter J., Green, Dawn, Jeddeloh, Jeffrey, Richmond, Todd, Rosenbaum, Heidi, Burgess, Daniel, Springer, Nathan M., Greally, John M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Methods Online
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499119/
https://ncbi.nlm.nih.gov/pubmed/25813045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv244
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