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Development and Validation of an UPLC-MS/MS Assay for Quantitative Analysis of the Ghrelin Receptor Inverse Agonist PF-5190457 in Human or Rat Plasma and Rat Brain

PF-5190457 is a ghrelin receptor inverse agonist that is currently undergoing clinical development for the treatment of alcoholism. Our aim was to develop and validate a simple and sensitive assay for quantitative analysis of PF-5190457 in human or rat plasma and rat brain using liquid chromatograph...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Anal Bioanal Chem
Κύριοι συγγραφείς: Ghareeb, Mwlod, Leggio, Lorenzo, El-Kattan, Ayman, Akhlaghi, Fatemeh
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499019/
https://ncbi.nlm.nih.gov/pubmed/25943263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-015-8730-2
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