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Genetic Polymorphism at Val(80) (rs700518) of the CYP19A1 Gene is Associated with Body Composition Changes in Women on Aromatase Inhibitors for ER (+) Breast Cancer

PURPOSE: Polymorphisms in the CYP19A1 (aromatase) gene influence disease-free survival and bone loss in patients taking aromatase inhibitors (AIs) for estrogen receptor positive (ER+) breast cancers. Because AI use results in profound estrogen deficiency which may lead to changes in body composition...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharmacogenet Genomics
Prif Awduron: Napoli, Nicola, Rastelli, Antonella, Ma, Cynthia, Colleluori, Georgia, Vattikuti, Swapna, Armamento-Villareal, Reina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498982/
https://ncbi.nlm.nih.gov/pubmed/26049585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000146
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