Genetic Polymorphism at Val(80) (rs700518) of the CYP19A1 Gene is Associated with Aromatase Inhibitor Associated Bone Loss in Women with ER (+) Breast Cancer

PURPOSE: Polymorphisms in the CYP19A1 (aromatase) gene have been reported to influence disease-free survival and the incidence of musculoskeletal complaints in patients taking aromatase inhibitors (AIs) for estrogen receptor positive (ER+) breast cancer. Bone loss and fractures are wellrecognized co...

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Main Authors: Napoli, Nicola, Rastelli, Antonella, Ma, Cynthia, Yarramaneni, Jayasree, Vattikutti, Swapna, Moskowitz, Gerard, Giri, Tusar, Mueller, Cheryl, Kulkarny, Vibhati, Qualls, Clifford, Ellis, Matthew, Armamento-Villareal, Reina
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966714/
https://ncbi.nlm.nih.gov/pubmed/23643682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2013.04.021
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