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Surviving hypoxia by modulation of mRNA translation rate

Cells can survive hypoxia/anoxia by metabolic rate depression, which involves lowering of mRNA translation rates in an ATP-dependent manner. By activating anaerobic ATP production (glycolysis), the inhibitory influence on mRNA translation in hypoxia can be abolished. In severe hypoxia, glycolysis ca...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Autor principal: Fähling, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498934/
https://ncbi.nlm.nih.gov/pubmed/19674191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00875.x
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