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Geometry of the Gene Expression Space of Individual Cells

There is a revolution in the ability to analyze gene expression of single cells in a tissue. To understand this data we must comprehend how cells are distributed in a high-dimensional gene expression space. One open question is whether cell types form discrete clusters or whether gene expression for...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Korem, Yael, Szekely, Pablo, Hart, Yuval, Sheftel, Hila, Hausser, Jean, Mayo, Avi, Rothenberg, Michael E., Kalisky, Tomer, Alon, Uri
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498931/
https://ncbi.nlm.nih.gov/pubmed/26161936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004224
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