Immediate Epileptogenesis after Kainate-Induced Status Epilepticus in C57BL/6J Mice: Evidence from Long Term Continuous Video-EEG Telemetry

The C57BL/6J mouse as a model of seizure/epilepsy is challenging due to high mortality and huge variability in response to kainate. We have recently demonstrated that repeated administration of a low dose of kainate by intraperitoneal route can induce severe status epilepticus (SE) with 94% survival...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Puttachary, Sreekanth, Sharma, Shaunik, Tse, Karen, Beamer, Edward, Sexton, Abby, Crutison, Joseph, Thippeswamy, Thimmasettappa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498886/
https://ncbi.nlm.nih.gov/pubmed/26161754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131705
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