PINK1-Parkin-Mediated Mitophagy Protects Mitochondrial Integrity and Prevents Metabolic Stress-Induced Endothelial Injury

Mitochondrial injury and dysfunction, a significant feature in metabolic syndrome, triggers endothelial cell dysfunction and cell death. Increasing evidence suggests that mitophagy, a process of autophagic turnover of damaged mitochondria, maintains mitochondrial integrity. PINK1 (phosphatase and te...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wu, Weiwei, Xu, Hao, Wang, Zemin, Mao, Yun, Yuan, Liangshuai, Luo, Wei, Cui, Zhaoqiang, Cui, Taixing, Wang, Xing Li, Shen, Ying H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498619/
https://ncbi.nlm.nih.gov/pubmed/26161534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132499
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