Histone Deacetylase Inhibitor Romidepsin Has Differential Activity in Core Binding Factor Acute Myeloid Leukemia

PURPOSE: Recruitment of histone deacetylases (HDAC) is a mechanism of transcriptional repression implicated in the differentiation block in acute myeloid leukemia (AML). We hypothesized that the HDAC inhibitor romidepsin could cause transcriptional derepression, up-regulation of specific target gene...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Odenike, Olatoyosi M., Alkan, Serhan, Sher, Dorie, Godwin, John E., Huo, Dezheng, Brandt, Stephen J., Green, Margaret, Xie, Jingping, Zhang, Yanming, Vesole, David H., Stiff, Patrick, Wright, John, Larson, Richard A., Stock, Wendy
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498482/
https://ncbi.nlm.nih.gov/pubmed/18981008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1007
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker