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PPARα and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal
Many acute and chronic anemias, including hemolysis, sepsis, and genetic bone marrow failure diseases such as Diamond-Blackfan Anemia (DBA), are not treatable with erythropoietin (Epo), because the colony-forming unit erythroid progenitors (CFU-Es) that respond to Epo are either too few in number or...
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| Publié dans: | Nature |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4498266/ https://ncbi.nlm.nih.gov/pubmed/25970251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14326 |
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