Leptin administration restores the altered adipose and hepatic expression of aquaglyceroporins improving the non-alcoholic fatty liver of ob/ob mice

Glycerol is an important metabolite for the control of lipid accumulation in white adipose tissue (WAT) and liver. We aimed to investigate whether exogenous administration of leptin improves features of non-alcoholic fatty liver disease (NAFLD) in leptin-deficient ob/ob mice via the regulation of AQ...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rodríguez, Amaia, Moreno, Natalia R., Balaguer, Inmaculada, Méndez-Giménez, Leire, Becerril, Sara, Catalán, Victoria, Gómez-Ambrosi, Javier, Portincasa, Piero, Calamita, Giuseppe, Soveral, Graça, Malagón, María M., Frühbeck, Gema
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498231/
https://ncbi.nlm.nih.gov/pubmed/26159457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12067
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