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NEXN inhibits GATA4 and leads to atrial septal defects in mice and humans
AIMS: Cardiac structural genes have been implicated as causative factors for congenital heart diseases (CHDs). NEXN is an F-actin binding protein and previously identified as a disease gene causing cardiomyopathies. Whether NEXN contributes to CHDs aetiologically remains unknown. Here, we explored t...
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Yayımlandı: | Cardiovasc Res |
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Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Oxford University Press
2014
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4498134/ https://ncbi.nlm.nih.gov/pubmed/24866383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu134 |
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