Mutational screening of affected cardiac tissues and peripheral blood cells identified novel somatic mutations in GATA4 in patients with ventricular septal defect()

The aim of this study was to examine how somatic mutations of the GATA4 gene contributed to the genesis of ventricular septal defect (VSD). The coding and intron-exon boundary regions of GATA4 were sequenced of DNA samples from peripheral blood cells and cardiac tissues of twenty surgically treated...

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Detalhes bibliográficos
Main Authors: Cheng, Chunyan, Lin, Yuan, Yang, Fan, Wang, Wenjing, Wu, Chong, Qin, Jingli, Shao, Xiuqin, Zhou, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Department of Journal of Biomedical Research 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596722/
https://ncbi.nlm.nih.gov/pubmed/23554720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1674-8301(11)60056-0
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