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4E-BPs Control Fat Storage by Regulating the Expression of Egr1 and ATGL

Early growth response transcription factor Egr1 controls multiple aspects of cell physiology and metabolism. In particular, Egr1 suppresses lipolysis and promotes fat accumulation in adipocytes by inhibiting the expression of adipose triglyceride lipase. According to current dogma, regulation of the...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Singh, Maneet, Shin, Yu-Kyong, Yang, Xiaoqing, Zehr, Brad, Chakrabarti, Partha, Kandror, Konstantin V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498071/
https://ncbi.nlm.nih.gov/pubmed/25814662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631895
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