SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL

Recent studies have established SIRT1 as an important regulator of lipid metabolism, although the mechanism of its action at the molecular level has not been revealed. Here, we show that knockdown of SIRT1 with the help of small hairpin RNA decreases basal and isoproterenol-stimulated lipolysis in c...

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Bibliografische gegevens
Hoofdauteurs: Chakrabarti, Partha, English, Taylor, Karki, Shakun, Qiang, Li, Tao, Rong, Kim, Juyoun, Luo, Zhijun, Farmer, Stephen R., Kandror, Konstantin V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2011
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151689/
https://ncbi.nlm.nih.gov/pubmed/21743036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M014647
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