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SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL

Recent studies have established SIRT1 as an important regulator of lipid metabolism, although the mechanism of its action at the molecular level has not been revealed. Here, we show that knockdown of SIRT1 with the help of small hairpin RNA decreases basal and isoproterenol-stimulated lipolysis in c...

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書誌詳細
主要な著者: Chakrabarti, Partha, English, Taylor, Karki, Shakun, Qiang, Li, Tao, Rong, Kim, Juyoun, Luo, Zhijun, Farmer, Stephen R., Kandror, Konstantin V.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151689/
https://ncbi.nlm.nih.gov/pubmed/21743036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M014647
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