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Insights into disease-associated mutations in the human proteome through protein structural analysis
Most known disease-associated mutations are missense mutations involving changes of amino acids of proteins encoded by their genes. Given the plethora of genetic studies, sequenced exomes, and new protein structures determined each year, it is appropriate to revisit the role that structure plays in...
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| Pubblicato in: | Structure |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4497952/ https://ncbi.nlm.nih.gov/pubmed/26027735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.03.028 |
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