Suppression of NLRX1 in chronic obstructive pulmonary disease

Cigarette smoke (CS) and viruses promote the inflammation and remodeling associated with chronic obstructive pulmonary disease (COPD). The MAVS/RIG-I–like helicase (MAVS/RLH) pathway and inflammasome-dependent innate immune pathways are important mediators of these responses. At baseline, the MAVS/R...

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Gepubliceerd in:J Clin Invest
Hoofdauteurs: Kang, Min-Jong, Yoon, Chang Min, Kim, Bo Hye, Lee, Chang-Min, Zhou, Yang, Sauler, Maor, Homer, Rober, Dhamija, Anish, Boffa, Daniel, West, Andrew Phillip, Shadel, Gerald S., Ting, Jenny P., Tedrow, John R., Kaminski, Naftali, Kim, Woo Jin, Lee, Chun Geun, Oh, Yeon-Mok, Elias, Jack A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2015
Onderwerpen:
Brief Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497738/
https://ncbi.nlm.nih.gov/pubmed/25938787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71747
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