OPCML is frequently methylated in human colorectal cancer and its restored expression reverses EMT via downregulation of smad signaling

Emerging evidence has indicated that the expression of OPCML gene is frequently altered in a variety of cancers. We previously demonstrated that the OPCML gene is a target of epigenetic inactivation and its gene product exhibits tumor-suppressive properties. However, little is known regarding the ef...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Li, Chunhong, Tang, Liping, Zhao, Lijuan, Li, Lili, Xiao, Qian, Luo, Xinrong, Peng, Weiyan, Ren, Guosheng, Tao, Qian, Xiang, Tingxiu
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497432/
https://ncbi.nlm.nih.gov/pubmed/26175934
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