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Effects of dose rates on radiation-induced replenishment of intestinal stem cells determined by Lgr5 lineage tracing

An understanding of the dynamics of intestinal Lgr5(+) stem cells is important for elucidating the mechanism of colonic cancer development. We previously established a method for evaluating Lgr5(+) stem cells by tamoxifen-dependent Lgr5-lineage tracing and showed that high-dose-rate radiation stimul...

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Dades bibliogràfiques
Publicat a:J Radiat Res
Autors principals: Otsuka, Kensuke, Iwasaki, Toshiyasu
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497386/
https://ncbi.nlm.nih.gov/pubmed/25832104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrv012
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