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Vitamin D is a determinant of mouse intestinal Lgr5 stem cell functions
Lgr5+ intestinal crypt base columnar cells function as stem cells whose progeny populate the villi, and Lgr5+ cells in which Apc is inactivated can give rise to tumors. Surprisingly, these Lgr5+ stem cell properties were abrogated by the lower dietary vitamin D and calcium in a semi-purified diet th...
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| Publicado no: | Carcinogenesis |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303796/ https://ncbi.nlm.nih.gov/pubmed/25344836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu221 |
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