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Injecting engineered anti-inflammatory macrophages therapeutically induces white adipose tissue browning and improves diet-induced insulin resistance

We recently exploited a transgenic approach to coerce macrophage anti-inflammatory M2 polarization in vivo by lowering Receptor Interacting Protein 140 (RIP140) level in macrophages (mφRIP140KD), which induced browning of white adipose tissue (WAT). In vitro, conditioned medium from cultured adipose...

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Bibliographic Details
Published in:Adipocyte
Main Authors: Liu, Pu-Ste, Lin, Yi-Wei, Burton, Frank H, Wei, Li-Na
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497295/
https://ncbi.nlm.nih.gov/pubmed/26167415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21623945.2014.981438
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