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NF-κB p50 facilitates neutrophil accumulation during LPS-induced pulmonary inflammation

BACKGROUND: Transcription factors have distinct functions in regulating immune responses. During Escherichia coli pneumonia, deficiency of NF-κB p50 increases gene expression and neutrophil recruitment, suggesting that p50 normally limits these innate immune responses. p50-deficient mice were used t...

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Detalhes bibliográficos
Main Authors: Mizgerd, Joseph P, Lupa, Michal M, Spieker, Matt S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC449706/
https://ncbi.nlm.nih.gov/pubmed/15189567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-5-10
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