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Glucose starvation and hypoxia, but not the saturated fatty acid palmitic acid or cholesterol, activate the unfolded protein response in 3T3-F442A and 3T3-L1 adipocytes

Obesity is associated with endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) in adipose tissue. In this study we identify physiological triggers of ER stress and of the UPR in adipocytes in vitro. We show that two markers of adipose tissue remodelling in obesity...

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Publicat a:Adipocyte
Autors principals: Mihai, Adina D, Schröder, Martin
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496967/
https://ncbi.nlm.nih.gov/pubmed/26257992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21623945.2014.989728
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