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Focal segmental glomerulosclerosis: molecular genetics and targeted therapies

Recent advances show that human focal segmental glomerulosclerosis (FSGS) is a primary podocytopathy caused by podocyte-specific gene mutations including NPHS1, NPHS2, WT-1, LAMB2, CD2AP, TRPC6, ACTN4 and INF2. This review focuses on genes discovered in the investigation of complex FSGS pathomechani...

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Bibliografiska uppgifter
I publikationen:BMC Nephrol
Huvudupphovsmän: Chen, Ying Maggie, Liapis, Helen
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496884/
https://ncbi.nlm.nih.gov/pubmed/26156092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-015-0090-9
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