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Focal segmental glomerulosclerosis: molecular genetics and targeted therapies
Recent advances show that human focal segmental glomerulosclerosis (FSGS) is a primary podocytopathy caused by podocyte-specific gene mutations including NPHS1, NPHS2, WT-1, LAMB2, CD2AP, TRPC6, ACTN4 and INF2. This review focuses on genes discovered in the investigation of complex FSGS pathomechani...
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| Publié dans: | BMC Nephrol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4496884/ https://ncbi.nlm.nih.gov/pubmed/26156092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-015-0090-9 |
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