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Caspr2 autoantibodies target multiple epitopes

OBJECTIVE: To better understand the mechanisms of autoantibodies to the axonal protein contactin-associated protein-like 2 (Caspr2) by studying their target epitopes. METHODS: A plasmid for expressing Caspr2 was modified so that the various extracellular subdomains were deleted individually and in g...

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Dettagli Bibliografici
Pubblicato in:Neurol Neuroimmunol Neuroinflamm
Autori principali: Olsen, Abby L., Lai, Yongjie, Dalmau, Josep, Scherer, Steven S., Lancaster, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496632/
https://ncbi.nlm.nih.gov/pubmed/26185774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000127
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