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Inhibitory axons are targeted in hippocampal cell culture by anti-Caspr2 autoantibodies associated with limbic encephalitis
Contactin-associated protein-like 2 (Caspr2), also known as CNTNAP2, is a cell adhesion molecule that clusters voltage-gated potassium channels (Kv1.1/1.2) at the juxtaparanodes of myelinated axons and may regulate axonal excitability. As a component of the Kv1 complex, Caspr2 has been identified as...
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Publicado no: | Front Cell Neurosci |
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Principais autores: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4496579/ https://ncbi.nlm.nih.gov/pubmed/26217189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00265 |
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