IgG Antibodies to Endothelial Protein C Receptor-Binding Cysteine-Rich Interdomain Region Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 Are Acquired Early in Life in Individuals Exposed to Malaria

Severe malaria syndromes are precipitated by Plasmodium falciparum parasites binding to endothelial receptors on the vascular lining. This binding is mediated by members of the highly variant P. falciparum erythrocyte membrane protein 1 (PfEMP1) family. We have previously identified a subset of PfEM...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Turner, Louise, Lavstsen, Thomas, Mmbando, Bruno P., Wang, Christian W., Magistrado, Pamela A., Vestergaard, Lasse S., Ishengoma, Deus S., Minja, Daniel T. R., Lusingu, John P., Theander, Thor G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496620/
https://ncbi.nlm.nih.gov/pubmed/26015475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00271-15
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